Hey Everyone!

I’ve been getting a lot of questions from customers about the differences between our Broccoli Juice Powder and Aguaje Powder, and which one is better for balancing hormones.

One is not really better than the other. Aguaje and broccoli juice powder are like the two most powerful warriors working together preventing hormonal chaos through unique mechanisms, making them complementary when used together.

Let me explain.

While it’s fresh in your mind, let’s go over again how estrogen works, and then we’ll go over the mechanisms of action of each superfood.

In both men and women, excess estrogen is the main cause of hormonal mayhem.

When estrogen is first naturally created in the body, it’s not a problem. After estrogen is produced, it binds to estrogen receptors in various tissues to exert its biological effects. Afterwards, the estrogen goes to the liver and gets transformed into various metabolites, making it easier to eliminate from the body.

The two main metabolites that Estrogen is converted to in the liver is:

2-hydroxyestrone (beneficial to the human body)
16α-hydroxyestrone (harmful to the human body)

60-70% of estrogen is converted to 2-hydroxyestrone, and 20-30% of estrogen is converted to 16α-hydroxyestrone.

After estrogen converts into these two estrogen metabolites, the 2-hydroxyestrone creates beneficial reactions and the 16α-hydroxyestrone causes chaos in the body.

16α-hydroxyestrone is a harmful estrogen metabolite that forms reactive oxygen species (ROS) and binds irreversibly to DNA, which can lead to mutations, inflammation, and an increased risk of hormone-related cancers. Its strong estrogenic effects stimulate cell proliferation, and when produced in excess, it can promote uncontrolled cell division, tumor growth, and tumor progression, making it a significant contributor to cancer development and other estrogen-dominant conditions.

2-hydroxyestrone is generally considered protective. It has weak estrogenic activity, doesn't bind strongly to receptors, and doesn’t form harmful DNA adducts or reactive compounds. Instead, it supports safe estrogen clearance, helps counteract stronger estrogens, and may even have anti-cancer and anti-inflammatory effects during metabolism and elimination.

So, the broccoli juice powder will make it so the body makes more of the beneficial 2-hydroxyestrone versus the more harmful 16α-hydroxyestrone .

Aguaje, on the other hand, is rich in phytoestrogens that bind to estrogen receptors with lower potency—similar to the mild, protective effects of 2-hydroxyestrone—as opposed to the stronger, more harmful metabolite 16α-hydroxyestrone. By mimicking 2-hydroxyestrone, Aguaje competes at the receptor with 16α-hydroxyestrone, thereby reducing estrogen overstimulation and its disruptive effects on the body. In essence, taking Aguaje is like boosting your body’s levels of the gentler, protective form of estrogen 2-hydroxyestrone.

So the broccoli juice powder makes it so more estrogen is converted into 2-hydroxyestrone versus the harmful 16α-hydroxyestrone, and aguaje just throws in more Phytoestrogens soldiers that mimic 2-hydroxyestrone competing at estrogen receptors with the harmful 16α-hydroxyestrone that are still present making the harmful 16α-hydroxyestrone less active.

The two together are the most powerful natural combination one can use in order to balance our hormone system.

In a perfect world where the body produces a normal amount of estrogen, then it's easy for the body to handle this 2:1 ratio of 2-hydroxyestrone to 16α-hydroxyestrone without a problem. However, as we age, and with the issues in today's day and age, it's much easier to produce excess estrogen, which creates more of the harmful estrogen metabolite (16α-hydroxyestrone).

Factors that increase estrogen in both men and women include excess fat, xenoestrogens (like BPA), chronic stress, poor diet, and sedentary lifestyle, increasing the risks associated with estrogen dominance.

Aging in both men and women can also increase estrogen levels, which increases the production of 16α-hydroxyestrone. In women, this is particularly evident during perimenopause and menopause, when reduced liver function, changes in hormone production, and decreased detoxification capacity contribute to the shift. In men, a decline in testosterone levels and increased aromatase activity convert more testosterone into estrogen, promoting 16α-hydroxyestrone.

In women, excess estrogen activity overstimulates tissues, causes fluid retention, and disrupts normal hormonal signaling, causing bloating, headaches/migraines, weight gain, especially around hips/thighs, fatigue, mood swings, irritability, anxiety, depression, breast tenderness and swelling, painful periods, and increased PMS symptoms.

In men, excess estrogen, which includes excess 16α-hydroxyestrone, can affect the balance between estrogen and testosterone, leading to reduced libido, sexual dysfunction, erectile dysfunction, decreased muscle mass, increased body fat, especially in the chest or abdominal area, mood swings, irritability, fatigue, and development of breast tissue.

The Broccoli Juice Powder and Aguaje Powder will help the body process any of this harmful excess estrogen.

The broccoli juice powder will make it so more of the beneficial 2-hydroxyestrone is produced versus more of the harmful 16α-hydroxyestrone, and the Aguaje will mimic the beneficial 2-hydroxyestrone, producing milder and more protective actions, which competes at estrogen receptors against the harmful 16α-hydroxyestrone that is still present in the body.

Both of these Superfoods together are the most powerful and potent natural foods one can take to combat excess estrogen activity that causes unwanted hormonal chaos in the human body.

I hope that clears everything up.

If you are interested in ordering our Broccoli Juice or Aguaje Powder, click the link below:
https://therawfoodworld.com/product-category/at-cost/

Thanks everyone for your support!

Sincerely,

Matt